MovDisordV3, Main, Exploration, bibRecord, 004013

Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study

Identifieur interne : 004013 ( Main/Exploration ); précédent : 004012; suivant : 004014

Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study

Auteurs : Bechir Jarraya [France] ; Anne-Marie Bonnet [France] ; Charles Duyckaerts [France] ; Jean-Luc Houeto [France] ; Philippe Cornu [France] ; Jean-Jacques Hauw [France] ; Yves Agid [France]

Source :

Movement Disorders [ 0885-3185 ] ; 2003-12.

RBID : ISTEX:9C7A8C4B14DAAE696BC221EB779B4ACCF6AD3E7B

Descripteurs français

Pascal (Inist)
- Critère sélection, Etude cas, Femelle, Indication, Noyau sousthalamique, Parkinson maladie, Personne âgée, Pronostic, Stimulus électrique, Traitement instrumental.
Wicri :
- topic : Personne âgée.

English descriptors

KwdEn :
- Aged, Antiparkinson Agents (adverse effects), Case study, Cognition Disorders (diagnosis), Disease Progression, Dyskinesia, Drug-Induced (etiology), Elderly, Electric Stimulation Therapy (instrumentation), Electrical stimulus, Fatal Outcome, Female, Humans, Indication, Instrumentation therapy, Levodopa (adverse effects), Neuropsychological Tests, Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson Disease (therapy), Parkinson disease, Parkinson's disease, Prognosis, Selection criterion, Subthalamic Nucleus (physiology), Subthalamic nucleus, Tremor (physiopathology), axial symptoms, neuropathology, subthalamic stimulation.
MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- diagnosis : Cognition Disorders.
- drug therapy : Parkinson Disease.
- etiology : Dyskinesia, Drug-Induced.
- instrumentation : Electric Stimulation Therapy.
- physiology : Subthalamic Nucleus.
- physiopathology : Parkinson Disease, Tremor.
- therapy : Parkinson Disease.
- Aged, Disease Progression, Fatal Outcome, Female, Humans, Neuropsychological Tests.

Abstract

We report on a patient with Parkinson's disease (PD) who was moderately improved by stimulation of the subthalamic nucleus (STN) and died 2 years after electrode implantation. After neurosurgery, symptoms that had responded to levodopa treatment preoperatively continued to improve. Postural instability, dysarthria, and cognitive impairment continued to worsen, despite STN stimulation and levodopa treatment. Postmortem examination of the brain confirmed the diagnosis of PD and showed that the electrodes had been correctly positioned within the STN. The failure of STN stimulation in this patient confirms the importance of screening and excluding patients from surgery with evolving parkinsonian axial symptoms or cognitive impairment. © 2003 Movement Disorder Society

Url:

https://api.istex.fr/document/9C7A8C4B14DAAE696BC221EB779B4ACCF6AD3E7B/fulltext/pdf

DOI: 10.1002/mds.10607

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">We report on a patient with Parkinson's disease (PD) who was moderately improved by stimulation of the subthalamic nucleus (STN) and died 2 years after electrode implantation. After neurosurgery, symptoms that had responded to levodopa treatment preoperatively continued to improve. Postural instability, dysarthria, and cognitive impairment continued to worsen, despite STN stimulation and levodopa treatment. Postmortem examination of the brain confirmed the diagnosis of PD and showed that the electrodes had been correctly positioned within the STN. The failure of STN stimulation in this patient confirms the importance of screening and excluding patients from surgery with evolving parkinsonian axial symptoms or cognitive impairment. © 2003 Movement Disorder Society</div>
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Movement Disorders (revue)

Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study

Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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	Movement Disorders (revue)
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